RNA-Sequencing, Connectivity Mapping, and Molecular Docking to Investigate Ligand-Protein Binding for Potential Drug Candidates for the Treatment of Wilms Tumor

BACKGROUND: Wilms tumor, or nephroblastoma, is a malignant pediatric embryonal renal tumor that has a poor prognosis. This study aimed to use bioinformatics data, RNA-sequencing, connectivity mapping, molecular docking, and ligand-protein binding to identify potential targets for drug therapy in Wil...

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Detalles Bibliográficos
Autores principales: Luo, Jia-Yuan, Yan, Shi-Bai, Chen, Gang, Chen, Peng, Liang, Song-Wu, Xu, Qiong-Qian, Gu, Jin-Han, Huang, Zhi-Guang, Qin, Li-Ting, Lu, Hui-Ping, Mo, Wei-Jia, Luo, Yi-Ge, Chen, Jia-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Database Analysis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119447/
https://www.ncbi.nlm.nih.gov/pubmed/32214060
http://dx.doi.org/10.12659/MSM.920725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119447/
https://www.ncbi.nlm.nih.gov/pubmed/32214060
http://dx.doi.org/10.12659/MSM.920725

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