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T-lymphocyte recognition of a portion of myelin basic protein encoded by an exon expressed during myelination

The major isoform of myelin basic protein (MBP) in the healthy adult central nervous system is the 18.5-kDa protein which is produced by mRNA derived from exons 1, 3, 4, 5, 6 and 7 of the MBP gene. Since isoforms containing exon 2-encoded protein (X2MBP) are expressed during myelin formation, we exa...

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Detalles Bibliográficos
Autores principales: Voskuhl, Rhonda R., McFarlin, Dale E., Stone, Roger, McFarland, Henry F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119506/
https://www.ncbi.nlm.nih.gov/pubmed/7679118
http://dx.doi.org/10.1016/0165-5728(93)90009-N