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Determination of affinities of a panel of IgGs and Fabs for whole enveloped (influenza A) virions using surface plasmon resonance

The affinity of a panel of neutralizing monoclonal IgGs and their Fab fragments has been measured for the first time with an enveloped type A influenza virus, by surface plasmon resonance (SPR) and the BIAlite(™) instrument. Equilibrium constants could be calculated for four of the five mAbs tested....

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Detalles Bibliográficos
Autores principales: Schofield, D.J., Dimmock, N.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119561/
https://www.ncbi.nlm.nih.gov/pubmed/8910646
http://dx.doi.org/10.1016/0166-0934(96)02086-1