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Interleukin-4 induces proliferation and activation of microglia but suppresses their induction of class II major histocompatibility complex antigen expression

We recently found that microglia, brain macrophages, express interleukin-4 (IL-4) receptor mRNA in vitro. Since IL-4 exhibits a variety of functions on the cells of monocyte-macrophage lineage, we examined the effects of IL-4on the functions of microglia. Recombinant IL-4 induced the proliferation o...

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Detalles Bibliográficos
Autores principales: Suzumura, Akio, Sawada, Makoto, Itoh, Yasuhiro, Marunouchi, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119647/
https://www.ncbi.nlm.nih.gov/pubmed/8071435
http://dx.doi.org/10.1016/0165-5728(94)90031-0