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Interleukin-4 induces proliferation and activation of microglia but suppresses their induction of class II major histocompatibility complex antigen expression
We recently found that microglia, brain macrophages, express interleukin-4 (IL-4) receptor mRNA in vitro. Since IL-4 exhibits a variety of functions on the cells of monocyte-macrophage lineage, we examined the effects of IL-4on the functions of microglia. Recombinant IL-4 induced the proliferation o...
Autores principales: | Suzumura, Akio, Sawada, Makoto, Itoh, Yasuhiro, Marunouchi, Tohru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
1994
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119647/ https://www.ncbi.nlm.nih.gov/pubmed/8071435 http://dx.doi.org/10.1016/0165-5728(94)90031-0 |
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