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Enhancement of the immunogenicity of an infectious bronchitis virus DNA vaccine by a bicistronic plasmid encoding nucleocapsid protein and interleukin-2

A DNA vaccine against infectious bronchitis virus (IBV) can induce specific humoral and cell-mediated immunity. However, compared to conventional vaccines, DNA vaccines usually induce poor antibody responses. To develop a more potent IBV DNA vaccine formulations, a monocistronic vector encoding the...

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Detalles Bibliográficos
Autores principales: Tang, Mengjun, Wang, Hongning, Zhou, Sheng, Tian, Guobao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119663/
https://www.ncbi.nlm.nih.gov/pubmed/18329109
http://dx.doi.org/10.1016/j.jviromet.2008.01.017