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Production of mice from a lethal coronavirus infection in the central nervous system by adoptive transfer of virus-specific T cell clones
The protective effect of a mouse hepatitis virus type-4 (MHV-4)-specific CD8(+) cytotoxic T cell clone and a CD4(+) helper T cell clone was examined by the adoptive transfer into brains of mice lethally infected with MHV-4. Mice survived acute encephalitis if more than 5 × 10(5) cells of either type...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Published by Elsevier B.V.
1991
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119813/ https://www.ncbi.nlm.nih.gov/pubmed/1705943 http://dx.doi.org/10.1016/0165-5728(91)90065-F |