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Delayed-type hypersensitivity response in the central nervous system during JHM virus infection requires viral specificity for protection

The JHM strain of mouse hepatitis virus (JHMV) elicits an I-A-restricted delayed-type hypersensitivity (DTH) response mediated by a Thy-1(+), Lyt-1(+), and CD4(+) T cell. Adoptive transfer of these polyclonal CD4(+) T cells from immunized mice prevents death in lethally infected recipients without s...

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Detalles Bibliográficos
Autores principales: Stohlman, Stephen A., Sussman, Mark A., Matsushima, Glenn K., Shubin, Richard A., Erlich, Stephanie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119880/
https://www.ncbi.nlm.nih.gov/pubmed/2842378
http://dx.doi.org/10.1016/0165-5728(88)90007-0