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Differential expression and regulation of major histocompatibility complex (MHC) products in neural and glial cells of the human fetal brain

The cells of the central nervous system (CNS) have the peculiarity of physiologically expressing very low levels of HLA molecules. In multiple sclerosis (MS), however, as in endocrine autoimmune diseases, there is a marked increase of HLA expression in the tissue (i.e. the plaques) and this is attri...

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Detalles Bibliográficos
Autores principales: Mauerhoff, Thekla, Pujol-Borrell, Ricardo, Mirakian, Rita, Bottazzo, Gian Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119889/
https://www.ncbi.nlm.nih.gov/pubmed/3133393
http://dx.doi.org/10.1016/0165-5728(88)90049-5