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Immortalization of Human B Cells: Analysis of B Cell Repertoire and Production of Human Monoclonal Antibodies
One of the major challenges in human B cell immunology field has been the objective to establish stable monoclonal cells lines that express the B cell receptor (BCR) on their cell surface and secrete antibodies. Such a system is extremely attractive not only for studying various aspect of BCR signal...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119954/ https://www.ncbi.nlm.nih.gov/pubmed/22723100 http://dx.doi.org/10.1007/978-1-61779-931-0_10 |