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Locked Nucleic Acid: High-Affinity Targeting of Complementary RNA for RNomics
Locked nucleic acid (LNA) is a nucleic acid analog containing one or more LNA nucleotide monomers with a bicyclic furanose unit locked in an RNA-mimicking sugar conformation. This conformational restriction is translated into unprecedented hybridization affinity towards complementary single-stranded...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120141/ https://www.ncbi.nlm.nih.gov/pubmed/16594628 http://dx.doi.org/10.1007/3-540-27262-3_21 |