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Monitoring Target Engagement of Deubiquitylating Enzymes Using Activity Probes: Past, Present, and Future
Deubiquitylating enzymes or DUBs are a class of enzymes that selectively remove the polypeptide posttranslational modification ubiquitin from a number of substrates. Approximately 100 DUBs exist in human cells and are involved in key regulatory cellular processes, which drive many disease states, ma...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120244/ https://www.ncbi.nlm.nih.gov/pubmed/27613052 http://dx.doi.org/10.1007/978-1-4939-3756-1_26 |