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Validity of patient-derived xenograft mouse models for lung cancer based on exome sequencing data

Patient-derived xenograft (PDX) mouse models are frequently used to test the drug efficacy in diverse types of cancer. They are known to recapitulate the patient characteristics faithfully, but a systematic survey with a large number of cases is yet missing in lung cancer. Here we report the compari...

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Detalles Bibliográficos
Autores principales: Kim, Jaewon, Rhee, Hwanseok, Kim, Jhingook, Lee, Sanghyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120347/
https://www.ncbi.nlm.nih.gov/pubmed/32224836
http://dx.doi.org/10.5808/GI.2020.18.1.e3