Manipulation of the Coronavirus Genome Using Targeted RNA Recombination with Interspecies Chimeric Coronaviruses

Targeted RNA recombination has proven to be a powerful tool for the genetic engineering of the coronavirus genome, particularly in its 3′ part. Here we describe procedures for the generation of recombinant and mutant mouse hepatitis virus and feline infectious peritonitis virus. Key to the two-step...

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Detalles Bibliográficos
Autores principales: de Haan, Cornelis A.M., Haijema, Bert Jan, Masters, Paul S., Rottier, Peter J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120397/
https://www.ncbi.nlm.nih.gov/pubmed/19057874
http://dx.doi.org/10.1007/978-1-59745-181-9_17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120397/
https://www.ncbi.nlm.nih.gov/pubmed/19057874
http://dx.doi.org/10.1007/978-1-59745-181-9_17

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