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Deficits in Motor Performance, Neurotransmitters and Synaptic Plasticity in Elderly and Experimental Parkinsonian Mice Lacking GPR37

Parkinson’s disease (PD) etiology is attributed to aging and the progressive neurodegeneration of dopamine (DA) neurons of substantia nigra pars compacta (SNc). GPR37 is an orphan G-protein Coupled Receptor (GPCR) that is linked to the juvenile form of PD. In addition, misfolded GPR37 has been found...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoqun, Mantas, Ioannis, Fridjonsdottir, Elva, Andrén, Per E., Chergui, Karima, Svenningsson, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120535/
https://www.ncbi.nlm.nih.gov/pubmed/32292338
http://dx.doi.org/10.3389/fnagi.2020.00084