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Pathological Aspects of Neuronal Hyperploidization in Alzheimer’s Disease Evidenced by Computer Simulation

When subjected to stress, terminally differentiated neurons are susceptible to reactivate the cell cycle and become hyperploid. This process is well documented in Alzheimer’s disease (AD), where it may participate in the etiology of the disease. However, despite its potential importance, the effects...

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Detalles Bibliográficos
Autores principales: Barrio-Alonso, Estíbaliz, Fontana, Bérénice, Valero, Manuel, Frade, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121139/
https://www.ncbi.nlm.nih.gov/pubmed/32292421
http://dx.doi.org/10.3389/fgene.2020.00287