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Oligonucleotide Therapeutics

The idea of sequence-specific gene silencing by synthetic oligonucleotides targeting mRNA is at least 40 years old, but it was only in the mid-1980s when technical advances made the chemical synthesis of oligonucleotides possible that practical steps could be taken toward its implementation. The res...

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Detalles Bibliográficos
Autores principales: Stein, Cy A., Hoehn, Britta, Rossi, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121153/
http://dx.doi.org/10.1007/978-1-4419-7358-0_20