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Generating Inhibitors of P-Glycoprotein: Where to, Now?

The prominent role for the drug efflux pump ABCB1 (P-glycoprotein) in mediating resistance to chemotherapy was first suggested in 1976 and sparked an incredible drive to restore the efficacy of anticancer drugs. Achieving this goal seemed inevitable in 1982 when a series of calcium channel blockers...

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Detalles Bibliográficos
Autores principales: Crowley, Emily, McDevitt, Christopher A., Callaghan, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121335/
https://www.ncbi.nlm.nih.gov/pubmed/19949934
http://dx.doi.org/10.1007/978-1-60761-416-6_18