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CLEC5A: A Promiscuous Pattern Recognition Receptor to Microbes and Beyond

CLEC5A is a spleen tyrosine kinase (Syk)-coupled C-type lectin that is highly expressed by monocytes, macrophages, neutrophils, and dendritic cells and interacts with virions directly, via terminal fucose and mannose moieties of viral glycans. CLEC5A also binds to N-acetylglucosamine (GlcNAc) and N-...

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Detalles Bibliográficos
Autores principales: Sung, Pei-Shan, Chang, Wei-Chiao, Hsieh, Shie-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121389/
https://www.ncbi.nlm.nih.gov/pubmed/32152943
http://dx.doi.org/10.1007/978-981-15-1580-4_3