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CLEC5A: A Promiscuous Pattern Recognition Receptor to Microbes and Beyond
CLEC5A is a spleen tyrosine kinase (Syk)-coupled C-type lectin that is highly expressed by monocytes, macrophages, neutrophils, and dendritic cells and interacts with virions directly, via terminal fucose and mannose moieties of viral glycans. CLEC5A also binds to N-acetylglucosamine (GlcNAc) and N-...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121389/ https://www.ncbi.nlm.nih.gov/pubmed/32152943 http://dx.doi.org/10.1007/978-981-15-1580-4_3 |