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Fidelity Variants and RNA Quasispecies

By now, it is well established that the error rate of the RNA-dependent RNA polymerase (RdRp) that replicates RNA virus genomes is a primary driver of the mutation frequencies observed in RNA virus populations—the basis for the RNA quasispecies. Over the last 10 years, a considerable amount of work...

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Detalles Bibliográficos
Autores principales: Bordería, Antonio V., Rozen-Gagnon, Kathryn, Vignuzzi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121553/
https://www.ncbi.nlm.nih.gov/pubmed/26499340
http://dx.doi.org/10.1007/82_2015_483