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An Overview on GPCRs and Drug Discovery: Structure-Based Drug Design and Structural Biology on GPCRs
G protein-coupled receptors (GPCRs) represent 50–60% of the current drug targets. There is no doubt that this family of membrane proteins plays a crucial role in drug discovery today. Classically, a number of drugs based on GPCRs have been developed for such different indications as cardiovascular,...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122359/ https://www.ncbi.nlm.nih.gov/pubmed/19513641 http://dx.doi.org/10.1007/978-1-60327-317-6_4 |