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Innate Resistance to Flavivirus Infections and the Functions of 2′-5′ Oligoadenylate Synthetases

Mouse susceptibility to experimental infections with flaviviruses is significantly influenced by a cluster of genes on chromosome 5 encoding a family of proteins with enzymatic properties, the 2′–5′ oligoadenylate synthetases (OAS). Positional cloning of the locus in question has revealed that susce...

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Detalles Bibliográficos
Autores principales: Mashimo, T., Simon-Chazottes, D., Guénet, J. -L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122621/
https://www.ncbi.nlm.nih.gov/pubmed/18727488
http://dx.doi.org/10.1007/978-3-540-75203-5_4