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Cell Entry of C3 Exoenzyme from Clostridium botulinum

Clostridium botulinum C3 is the prototype of C3-like ADP-ribosyltransferases that selectively ADP-ribosylate the small GTP-binding proteins RhoA/B/C and inhibit their downstream signaling pathways. It is used as pharmacological tool to study cellular Rho functions. In addition, C3bot harbors a trans...

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Detalles Bibliográficos
Autores principales: Rohrbeck, Astrid, Just, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122702/
https://www.ncbi.nlm.nih.gov/pubmed/27832378
http://dx.doi.org/10.1007/82_2016_44