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Low hemoglobin increases risk for cerebrovascular disease, kidney disease, pulmonary vasculopathy, and mortality in sickle cell disease: A systematic literature review and meta-analysis

Sickle cell disease (SCD) is characterized by deoxygenation–induced polymerization of hemoglobin in red blood cells, leading to hemolytic anemia, vaso–occlusion, and the development of multiple clinical complications. To characterize the clinical burden associated with differences in hemoglobin conc...

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Detalles Bibliográficos
Autores principales: Ataga, Kenneth I., Gordeuk, Victor R., Agodoa, Irene, Colby, Jennifer A., Gittings, Kimberly, Allen, Isabel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122773/
https://www.ncbi.nlm.nih.gov/pubmed/32243480
http://dx.doi.org/10.1371/journal.pone.0229959