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Low hemoglobin increases risk for cerebrovascular disease, kidney disease, pulmonary vasculopathy, and mortality in sickle cell disease: A systematic literature review and meta-analysis
Sickle cell disease (SCD) is characterized by deoxygenation–induced polymerization of hemoglobin in red blood cells, leading to hemolytic anemia, vaso–occlusion, and the development of multiple clinical complications. To characterize the clinical burden associated with differences in hemoglobin conc...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122773/ https://www.ncbi.nlm.nih.gov/pubmed/32243480 http://dx.doi.org/10.1371/journal.pone.0229959 |