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BRD4 inhibition exerts anti-viral activity through DNA damage-dependent innate immune responses

Chromatin dynamics regulated by epigenetic modification is crucial in genome stability and gene expression. Various epigenetic mechanisms have been identified in the pathogenesis of human diseases. Here, we examined the effects of ten epigenetic agents on pseudorabies virus (PRV) infection by using...

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Detalles Bibliográficos
Autores principales: Wang, Jiang, Li, Guo-Li, Ming, Sheng-Li, Wang, Chun-Feng, Shi, Li-Juan, Su, Bing-Qian, Wu, Hong-Tao, Zeng, Lei, Han, Ying-Qian, Liu, Zhong-Hu, Jiang, Da-Wei, Du, Yong-Kun, Li, Xiang-Dong, Zhang, Gai-Ping, Yang, Guo-Yu, Chu, Bei-Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122826/
https://www.ncbi.nlm.nih.gov/pubmed/32208449
http://dx.doi.org/10.1371/journal.ppat.1008429