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A 16-Step Synthesis of the Isoryanodane Diterpene (+)-Perseanol
(+)-Perseanol is an isoryanodane diterpene with potent antifeedant and insecticidal properties isolated from the tropical shrub Persea indica.(1) It is structurally related to (+)-ryanodine, a high affinity ligand and modulator of ryanodine receptors (RyRs)—ligand-gated ion channels critical for int...
Autores principales: | Han, Arthur, Tao, Yujia, Reisman, Sarah E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7123484/ https://www.ncbi.nlm.nih.gov/pubmed/31554978 http://dx.doi.org/10.1038/s41586-019-1580-x |
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