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TNF-alpha inhibitor adalimumab attenuates endotoxin induced cardiac damage in rats

PURPOSE: To investigate the effects of adalimumab pretreatment on the lipopolysaccharide-mediated myocardial injury. METHODS: Twenty-eight Wistar rats were randomized into four groups (n=7). Control (C) group animals were injected once a day with intraperitoneal (i.p) 0.9 % saline for two days. In t...

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Detalles Bibliográficos
Autores principales: Durmaz, Selim, Kurtoğlu, Tünay, Barbarus, Emin, Eliyatkın, Nükhet, Yılmaz, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124089/
https://www.ncbi.nlm.nih.gov/pubmed/32267288
http://dx.doi.org/10.1590/s0102-865020200020000002