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Essential Role of Syntaxin-Binding Protein-1 in the Regulation of Glucagon-Like Peptide-1 Secretion

Circadian secretion of the incretin, glucagon-like peptide-1 (GLP-1), correlates with expression of the core clock gene, Bmal1, in the intestinal L-cell. Several SNARE proteins known to be circadian in pancreatic α- and β-cells are also necessary for GLP-1 secretion. However, the role of the accesso...

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Detalles Bibliográficos
Autores principales: Campbell, Jhenielle R, Martchenko, Alexandre, Sweeney, Maegan E, Maalouf, Michael F, Psichas, Arianna, Gribble, Fiona M, Reimann, Frank, Brubaker, Patricia L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124137/
https://www.ncbi.nlm.nih.gov/pubmed/32141504
http://dx.doi.org/10.1210/endocr/bqaa039