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Unfolded protein response pathways regulate Hepatitis C virus replication via modulation of autophagy

BACKGROUND: Hepatitis C virus (HCV) induces endoplasmic reticulum (ER) stress which, in turn, activates the unfolding protein response (UPR). UPR activates three distinct signalling pathways. Additionally, UPR induces autophagy (UPR-autophagy pathways). On the other hand, it has become clear that so...

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Detalles Bibliográficos
Autores principales: Shinohara, Yoshiyasu, Imajo, Kento, Yoneda, Masato, Tomeno, Wataru, Ogawa, Yuji, Kirikoshi, Hiroyuki, Funakoshi, Kengo, Ikeda, Masanori, Kato, Nobuyuki, Nakajima, Atsushi, Saito, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124205/
https://www.ncbi.nlm.nih.gov/pubmed/23395875
http://dx.doi.org/10.1016/j.bbrc.2013.01.103