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Risk for HIV-1 infection is not associated with Repeat-Region polymorphism in the DC-SIGN neck domain and Novel Genetic DC-SIGN Variants among North Indians

BACKGROUND: Several genetic factors have been related to HIV-1 resistance, the homozygosity for a mutation in CCR5 gene (CCR5Δ 32 allele) is presently considered the most relevant one. The C-type lectin, DC-SIGN efficiently binds and transmits HIV-1 to susceptible cell in trans thereby augmenting th...

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Detalles Bibliográficos
Autores principales: Rathore, Anurag, Chatterjee, Animesh, Sood, Vikas, Khan, Sohrab Z., Banerjea, Akhil C., Yamamoto, Naohiko, Dhole, Tapan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124224/
https://www.ncbi.nlm.nih.gov/pubmed/18255039
http://dx.doi.org/10.1016/j.cca.2007.12.019