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Two specific membrane-bound aminopeptidase N isoforms from Aedes aegypti larvae serve as functional receptors for the Bacillus thuringiensis Cry4Ba toxin implicating counterpart specificity

The interaction between Bacillus thuringiensis Cry toxins and their receptors on midgut cells of susceptible insect larvae is the critical determinant in toxin specificity. Besides GPI-linked alkaline phosphatase in Aedes aegypti mosquito-larval midguts, membrane-bound aminopeptidase N (AaeAPN) is w...

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Detalles Bibliográficos
Autores principales: Aroonkesorn, Aratee, Pootanakit, Kusol, Katzenmeier, Gerd, Angsuthanasombat, Chanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124302/
https://www.ncbi.nlm.nih.gov/pubmed/25871797
http://dx.doi.org/10.1016/j.bbrc.2015.04.026