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In vitro and in vivo antimicrobial activity of two α-helical cathelicidin peptides and of their synthetic analogs

Two α-helical antimicrobial peptides (BMAP-27 and -28) and four synthetic analogs were compared for in vitro and in vivo antimicrobial efficacy. All peptides proved active in vitro at micromolar concentrations against a range of clinical isolates, including antibiotic-resistant strains. BMAP-27 and...

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Detalles Bibliográficos
Autores principales: Benincasa, Monica, Skerlavaj, Barbara, Gennaro, Renato, Pellegrini, Antonio, Zanetti, Margherita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124310/
https://www.ncbi.nlm.nih.gov/pubmed/15019203
http://dx.doi.org/10.1016/j.peptides.2003.07.025