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In vitro and in vivo antimicrobial activity of two α-helical cathelicidin peptides and of their synthetic analogs
Two α-helical antimicrobial peptides (BMAP-27 and -28) and four synthetic analogs were compared for in vitro and in vivo antimicrobial efficacy. All peptides proved active in vitro at micromolar concentrations against a range of clinical isolates, including antibiotic-resistant strains. BMAP-27 and...
Autores principales: | Benincasa, Monica, Skerlavaj, Barbara, Gennaro, Renato, Pellegrini, Antonio, Zanetti, Margherita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124310/ https://www.ncbi.nlm.nih.gov/pubmed/15019203 http://dx.doi.org/10.1016/j.peptides.2003.07.025 |
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