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Symmetry breaking in hydrodynamic forces drives meiotic spindle rotation in mammalian oocytes

Patterned cell divisions require a precisely oriented spindle that segregates chromosomes and determines the cytokinetic plane. In this study, we investigated how the meiotic spindle orients through an obligatory rotation during meiotic division in mouse oocytes. We show that spindle rotation occurs...

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Detalles Bibliográficos
Autores principales: Wang, HaiYang, Li, Yizeng, Yang, Jing, Duan, Xing, Kalab, Petr, Sun, Sean X., Li, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124937/
https://www.ncbi.nlm.nih.gov/pubmed/32284983
http://dx.doi.org/10.1126/sciadv.aaz5004