Selective and Wash‐Resistant Fluorescent Dihydrocodeinone Derivatives Allow Single‐Molecule Imaging of μ‐Opioid Receptor Dimerization

μ‐Opioid receptors (μ‐ORs) play a critical role in the modulation of pain and mediate the effects of the most powerful analgesic drugs. Despite extensive efforts, it remains insufficiently understood how μ‐ORs produce specific effects in living cells. We developed new fluorescent ligands based on th...

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Detalles Bibliográficos
Autores principales: Gentzsch, Christian, Seier, Kerstin, Drakopoulos, Antonios, Jobin, Marie‐Lise, Lanoiselée, Yann, Koszegi, Zsombor, Maurel, Damien, Sounier, Rémy, Hübner, Harald, Gmeiner, Peter, Granier, Sébastien, Calebiro, Davide, Decker, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125027/
https://www.ncbi.nlm.nih.gov/pubmed/31808251
http://dx.doi.org/10.1002/anie.201912683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125027/
https://www.ncbi.nlm.nih.gov/pubmed/31808251
http://dx.doi.org/10.1002/anie.201912683

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