Toll like-receptor agonist Pam(3)Cys modulates the immunogenicity of liposomes containing the tuberculosis vaccine candidate H56

A major roadblock in the development of novel vaccines is the formulation and delivery of the antigen. Liposomes composed of a dimethyldioctadecylammonium (DDA) backbone and the adjuvant trehalose-6-6-dibehenate (TDB, termed “cationic adjuvant formulation (CAF01)”, promote immunogenicity and protect...

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Detalles Bibliográficos
Autores principales: Kennerknecht, Kathrin, Noschka, Reiner, Löffler, Florian, Wehrstedt, Stephanie, Pedersen, Gabriel Kristian, Mayer, Daniel, Grieshober, Mark, Christensen, Dennis, Stenger, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125073/
https://www.ncbi.nlm.nih.gov/pubmed/32020284
http://dx.doi.org/10.1007/s00430-020-00657-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125073/
https://www.ncbi.nlm.nih.gov/pubmed/32020284
http://dx.doi.org/10.1007/s00430-020-00657-3

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