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Toll like-receptor agonist Pam(3)Cys modulates the immunogenicity of liposomes containing the tuberculosis vaccine candidate H56

A major roadblock in the development of novel vaccines is the formulation and delivery of the antigen. Liposomes composed of a dimethyldioctadecylammonium (DDA) backbone and the adjuvant trehalose-6-6-dibehenate (TDB, termed “cationic adjuvant formulation (CAF01)”, promote immunogenicity and protect...

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Detalles Bibliográficos
Autores principales:	Kennerknecht, Kathrin, Noschka, Reiner, Löffler, Florian, Wehrstedt, Stephanie, Pedersen, Gabriel Kristian, Mayer, Daniel, Grieshober, Mark, Christensen, Dennis, Stenger, Steffen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125073/ https://www.ncbi.nlm.nih.gov/pubmed/32020284 http://dx.doi.org/10.1007/s00430-020-00657-3

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