Transmembrane protein rotaxanes reveal kinetic traps in the refolding of translocated substrates

Understanding protein folding under conditions similar to those found in vivo remains challenging. Folding occurs mainly vectorially as a polypeptide emerges from the ribosome or from a membrane translocon. Protein folding during membrane translocation is particularly difficult to study. Here, we de...

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Detalles Bibliográficos
Autores principales: Feng, Jianfei, Martin-Baniandres, Pablo, Booth, Michael J., Veggiani, Gianluca, Howarth, Mark, Bayley, Hagan, Rodriguez-Larrea, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125113/
https://www.ncbi.nlm.nih.gov/pubmed/32246060
http://dx.doi.org/10.1038/s42003-020-0840-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125113/
https://www.ncbi.nlm.nih.gov/pubmed/32246060
http://dx.doi.org/10.1038/s42003-020-0840-5

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