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Transmembrane protein rotaxanes reveal kinetic traps in the refolding of translocated substrates
Understanding protein folding under conditions similar to those found in vivo remains challenging. Folding occurs mainly vectorially as a polypeptide emerges from the ribosome or from a membrane translocon. Protein folding during membrane translocation is particularly difficult to study. Here, we de...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125113/ https://www.ncbi.nlm.nih.gov/pubmed/32246060 http://dx.doi.org/10.1038/s42003-020-0840-5 |