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An oncopeptide regulates m(6)A recognition by the m(6)A reader IGF2BP1 and tumorigenesis

N(6)-methyladenosine (m(6)A) is the most prevalent modification in eukaryotic RNAs. The biological importance of m(6)A relies on m(6)A readers, which control mRNA fate and function. However, it remains unexplored whether additional regulatory subunits of m(6)A readers are involved in the m(6)A recog...

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Detalles Bibliográficos
Autores principales: Zhu, Song, Wang, Ji-Zhong, Chen, De, He, Yu-Tian, Meng, Nan, Chen, Min, Lu, Rui-Xun, Chen, Xin-Hui, Zhang, Xiao-Lan, Yan, Guang-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125119/
https://www.ncbi.nlm.nih.gov/pubmed/32245947
http://dx.doi.org/10.1038/s41467-020-15403-9