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METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice

Brown adipose tissue (BAT) undergoes rapid postnatal development and then protects against cold and obesity into adulthood. However, the molecular mechanism that determines postnatal development and maturation of BAT is largely unknown. Here we show that METTL3 (a key RNA methyltransferase) expressi...

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Detalles Bibliográficos
Autores principales: Wang, Yuqin, Gao, Ming, Zhu, Fuxing, Li, Xinzhi, Yang, Ying, Yan, Qiuxin, Jia, Linna, Xie, Liwei, Chen, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125133/
https://www.ncbi.nlm.nih.gov/pubmed/32245957
http://dx.doi.org/10.1038/s41467-020-15488-2