Translational derepression of Elavl4 isoforms at their alternative 5′ UTRs determines neuronal development

Neurodevelopment requires precise regulation of gene expression, including post-transcriptional regulatory events such as alternative splicing and mRNA translation. However, translational regulation of specific isoforms during neurodevelopment and the mechanisms behind it remain unknown. Using RNA-s...

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Detalles Bibliográficos
Autores principales: Popovitchenko, Tatiana, Park, Yongkyu, Page, Nicholas F., Luo, Xiaobing, Krsnik, Zeljka, Liu, Yuan, Salamon, Iva, Stephenson, Jessica D., Kraushar, Matthew L., Volk, Nicole L., Patel, Sejal M., Wijeratne, H. R. Sagara, Li, Diana, Suthar, Kandarp S., Wach, Aaron, Sun, Miao, Arnold, Sebastian J., Akamatsu, Wado, Okano, Hideyuki, Paillard, Luc, Zhang, Huaye, Buyske, Steven, Kostovic, Ivica, De Rubeis, Silvia, Hart, Ronald P., Rasin, Mladen-Roko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125149/
https://www.ncbi.nlm.nih.gov/pubmed/32245946
http://dx.doi.org/10.1038/s41467-020-15412-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125149/
https://www.ncbi.nlm.nih.gov/pubmed/32245946
http://dx.doi.org/10.1038/s41467-020-15412-8

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