Streamlined selection of cancer antigens for vaccine development through integrative multi-omics and high-content cell imaging

Identification of tumor antigens that induce cytotoxic T lymphocytes (CTLs) is crucial for cancer-vaccine development. Despite their predictive ability, current algorithmic approaches and human leukocyte antigen (HLA)-peptidomic analysis allow limited selectivity. Here, we optimized a method to rapi...

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Detalles Bibliográficos
Autores principales: Han, Ki-Cheol, Park, Daechan, Ju, Shinyeong, Lee, Young Eun, Heo, Sun-Hee, Kim, Young-Ae, Lee, Ji Eun, Lee, Yuna, Park, Kyong Hwa, Park, Se-Ho, Lee, Hee Jin, Lee, Cheolju, Jang, Mihue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125174/
https://www.ncbi.nlm.nih.gov/pubmed/32245999
http://dx.doi.org/10.1038/s41598-020-62244-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125174/
https://www.ncbi.nlm.nih.gov/pubmed/32245999
http://dx.doi.org/10.1038/s41598-020-62244-z

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