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Streamlined selection of cancer antigens for vaccine development through integrative multi-omics and high-content cell imaging
Identification of tumor antigens that induce cytotoxic T lymphocytes (CTLs) is crucial for cancer-vaccine development. Despite their predictive ability, current algorithmic approaches and human leukocyte antigen (HLA)-peptidomic analysis allow limited selectivity. Here, we optimized a method to rapi...
Autores principales: | Han, Ki-Cheol, Park, Daechan, Ju, Shinyeong, Lee, Young Eun, Heo, Sun-Hee, Kim, Young-Ae, Lee, Ji Eun, Lee, Yuna, Park, Kyong Hwa, Park, Se-Ho, Lee, Hee Jin, Lee, Cheolju, Jang, Mihue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125174/ https://www.ncbi.nlm.nih.gov/pubmed/32245999 http://dx.doi.org/10.1038/s41598-020-62244-z |
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