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Stem cell-derived polarized hepatocytes

Human stem cell-derived hepatocyte-like cells (HLCs) offer an attractive platform to study liver biology. Despite their numerous advantages, HLCs lack critical in vivo characteristics, including cell polarity. Here, we report a stem cell differentiation protocol that uses transwell filters to genera...

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Detalles Bibliográficos
Autores principales: Dao Thi, Viet Loan, Wu, Xianfang, Belote, Rachel L., Andreo, Ursula, Takacs, Constantin N., Fernandez, Joseph P., Vale-Silva, Luis Andre, Prallet, Sarah, Decker, Charlotte C., Fu, Rebecca M., Qu, Bingqian, Uryu, Kunihiro, Molina, Henrik, Saeed, Mohsan, Steinmann, Eike, Urban, Stephan, Singaraja, Roshni R., Schneider, William M., Simon, Sanford M., Rice, Charles M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125181/
https://www.ncbi.nlm.nih.gov/pubmed/32245952
http://dx.doi.org/10.1038/s41467-020-15337-2