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Stem cell-derived polarized hepatocytes
Human stem cell-derived hepatocyte-like cells (HLCs) offer an attractive platform to study liver biology. Despite their numerous advantages, HLCs lack critical in vivo characteristics, including cell polarity. Here, we report a stem cell differentiation protocol that uses transwell filters to genera...
Autores principales: | Dao Thi, Viet Loan, Wu, Xianfang, Belote, Rachel L., Andreo, Ursula, Takacs, Constantin N., Fernandez, Joseph P., Vale-Silva, Luis Andre, Prallet, Sarah, Decker, Charlotte C., Fu, Rebecca M., Qu, Bingqian, Uryu, Kunihiro, Molina, Henrik, Saeed, Mohsan, Steinmann, Eike, Urban, Stephan, Singaraja, Roshni R., Schneider, William M., Simon, Sanford M., Rice, Charles M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125181/ https://www.ncbi.nlm.nih.gov/pubmed/32245952 http://dx.doi.org/10.1038/s41467-020-15337-2 |
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