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High glucose induces phosphorylation and oxidation of mitochondrial proteins in renal tubular cells: A proteomics approach

Mitochondrial dysfunction has been thought to play roles in the pathogenesis of diabetic nephropathy (DN). However, precise mechanisms underlying mitochondrial dysfunction in DN remained unclear. Herein, mitochondria were isolated from renal tubular cells after exposure to normal glucose (5.5 mM glu...

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Detalles Bibliográficos
Autores principales: Aluksanasuwan, Siripat, Plumworasawat, Sirikanya, Malaitad, Thanyalak, Chaiyarit, Sakdithep, Thongboonkerd, Visith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125224/
https://www.ncbi.nlm.nih.gov/pubmed/32246012
http://dx.doi.org/10.1038/s41598-020-62665-w