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Improved drug carriage and protective potential against Cisplatin-induced toxicity using Boldine-loaded PLGA nanoparticles
BACKGROUND: Cisplatin is a widely-used potent anti-cancer drug having severe side-effects precluding its sustained use. OBJECTIVES: Poly (lactide-co-glycolide) (PLGA)-nanoparticles loaded Boldine, an antioxidant ingredient of ethanolic extract of Boldo plant (Peumus boldus) was tested in cancer mice...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125378/ https://www.ncbi.nlm.nih.gov/pubmed/30115410 http://dx.doi.org/10.1016/j.jaim.2017.11.002 |