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Targeted Therapy of Colon Cancer by Aptamer-Guided Holliday Junctions Loaded with Doxorubicin

PURPOSE: Chemotherapy is the primary treatment for advanced colon cancer, but its efficacy is often limited by severe toxicities. Targeted therapy in the form of selectively drug delivery system (SDDS) is an important strategy to reduce adverse effects. Here, we aim to design a novel SDDS with poten...

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Detalles Bibliográficos
Autores principales: Yao, Fengjiao, An, Yacong, Li, Xundou, Li, Zhaoyi, Duan, Jinhong, Yang, Xian-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125415/
https://www.ncbi.nlm.nih.gov/pubmed/32280210
http://dx.doi.org/10.2147/IJN.S240083